The AEROBIKA Oscillating Positive Expiratory Pressure (PEP) is a lightweight, hand-held device designed to aid in the loosening and removal of mucus build-up in the lungs. On exhalation, positive pressure builds up in the lungs – stinting the airways open. The pressure gets behind the mucus, helping push it out of the smaller airways. At the same time, the pulses (or oscillations) create vibrations within the airways helping to thin and shake loose mucus that may be too thick or sticky for the pressure alone to move. The combination of oscillations and pressure aids in moving mucus into the central airways, where it can be coughed out. Further, a 3 week patient-based trial showed our device also increased 6-minute walk distance, reduced dyspnea (breathlessness) and decreased cough frequency in a patient population who has few other drug-free treatment options. Patients with cystic fibrosis, COPD, Chronic bronchitis and bronchiectasis would benefit from Oscillatory PEP therapy in either a home or hospital environment.